https://www.ceesdekker.net Secrets
https://www.ceesdekker.net Secrets
Blog Article
‘Yes, that is certainly about ideal. I seek out a Actual physical understanding of biological devices inside of a bottom-up way. I believe you could distinguish 3 lines of analysis in my team in the meanwhile. The first concerns chromosome construction: how do you receive a metre-extended DNA polymer folded and organised in this type of microscopic cell? We have produced visualisation procedures that permit us to study how, such as, SMC proteins loop DNA (video clip on Youtube) in order to Develop up chromosomes.
Our team experiments bacterial mobile division and is also aiming to constitute a ‘base up biology’ in artificial cells which will autonomously divide. Our major curiosity lies in cell division, chromatin composition, and spatial Regulate.
Again in 1991, Sumio Iijima of your NEC Company experienced claimed the synthesis of carbon nanotubes. Band composition calculations suggested that these nanotubes could show metallic band conduction. This would be a significant advantage over the conducting polymers we had explored, which were, actually, disordered semiconductors supplying simply variable-variety hopping conductivity.
Our get the job done was immediately adopted up by Other people, most notably by Phaedon Avouris and colleagues at IBM, who in October 1998 released their conclusions on transistors comprised of one- and multi-walled carbon nanotubes in Applied Physics Letters.
2012, discovery that nucleoid occlusion underlies the accuracy of bacterial mobile division; and initial at any time research of the dynamics DNA supercoils and the invention of supercoil hopping
Our exploration ranges with the biophysics of DNA to artificial cells and outside of. You should take a look under with the spectrum of our recent assignments.
Many relevant developments followed, the place our team recognized unique transistor variants which include one-electron transistors at home temperature and intramolecular nanotube junctions that acted as rectifying diodes, and coupled various transistors into small evidence-of-basic principle Digital circuits.
Instance (1) of bending configurations in 3D simulations of DNA rods on nanopores. A percentage of the membrane is proven in grey, the rim on the pore is highlighted in crimson, plus a 3D rendering of your movement on the DNA rod is displayed.
The rotors harness Electrical power from the nanoscale water and ion flow that may be produced by a static chemical or electrochemical prospective gradient within the nanopore, which are founded by way of a salt gradient or applied voltage, respectively. These synthetic nanoengines self-organize and work autonomously in physiological ailments, suggesting approaches to constructing Vitality-transducing motors at nanoscale interfaces.
It had been all through this era that Dekker carried out study on magnetic spin programs and on sound in superconductors and semiconductors.
In 1993 he was appointed as Associate Professor at Delft University of Technological know-how. Inside the mid-nineteen nineties Dekker and his team attained results with the invention in the Digital Attributes of carbon nanotubes, the very first solitary-molecule transistor and various nanoscience.
2006, initially demonstration of molecular sorting in a lab on the chip working with cees dekker biomotors; discovery of nanobubbles in solid-condition nanopores; and initially estimate of electrokinetic energy conversion within a nanofluidic channel
Allow’s 1st glance again for the time being if you chose to change your concentration from superconductivity and nanotubes to biology at the conclusion of the nineteen nineties.
Supercoiling-dependent DNA binding: quantitative modeling and applications to bulk and one-molecule experiments